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Gene Editing and CRISPR Technology: Revolutionizing Biomedical Research

by Lina Khalifa 1,*
1
University of Jordan
*
Author to whom correspondence should be addressed.
JGSR  2023 5(1):66; https://doi.org/10.xxxx/xxxxxx
Received: 21 April 2023 / Accepted: 10 June 2023 / Published Online: 30 June 2023

Abstract

Gene editing and CRISPR technology have transformed the landscape of biomedical research by offering precise and targeted genetic modifications. This paper explores the significance of gene editing, emphasizing its role in disease treatment, genetic engineering, and biotechnology applications. It delves into various aspects, including CRISPR-Cas9 systems, gene therapy, and ethical considerations. The discussion includes the benefits of gene editing, such as potential cures for genetic disorders, enhanced crop yields, and novel therapeutic approaches. Moreover, the paper addresses the challenges and ethical dilemmas in gene editing, including off-target effects and responsible use. Through a review of gene editing studies and clinical trials, the study highlights the positive outcomes associated with the advancement of gene-editing technologies.


Copyright: © 2023 by Khalifa. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY) (Creative Commons Attribution 4.0 International License). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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ACS Style
Khalifa, L. Gene Editing and CRISPR Technology: Revolutionizing Biomedical Research. Journal of Globe Scientific Reports, 2023, 5, 66. doi:10.xxxx/xxxxxx
AMA Style
Khalifa L. Gene Editing and CRISPR Technology: Revolutionizing Biomedical Research. Journal of Globe Scientific Reports; 2023, 5(1):66. doi:10.xxxx/xxxxxx
Chicago/Turabian Style
Khalifa, Lina 2023. "Gene Editing and CRISPR Technology: Revolutionizing Biomedical Research" Journal of Globe Scientific Reports 5, no.1:66. doi:10.xxxx/xxxxxx

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References

  1. Doudna, J. A., & Charpentier, E. (2014). The new frontier of genome engineering with CRISPR-Cas9. Science, 346(6213), 1258096.
  2. Jinek, M., Chylinski, K., Fonfara, I., Hauer, M., Doudna, J. A., & Charpentier, E. (2012). A programmable dual-RNA–guided DNA endonuclease in adaptive bacterial immunity. Science, 337(6096), 816-821.
  3. Komor, A. C., Badran, A. H., & Liu, D. R. (2017). CRISPR-based technologies for the manipulation of eukaryotic genomes. Cell, 168(1-2), 20-36.
  4. Liang, P., Xu, Y., Zhang, X., Ding, C., Huang, R., Zhang, Z., ... & Songyang, Z. (2015). CRISPR/Cas9-mediated gene editing in human tripronuclear zygotes. Protein & Cell, 6(5), 363-372.
  5. Mout, R., Ray, M., Yesilbag Tonga, G., Lee, Y. W., Tay, T., Sasaki, K., ... & Rotello, V. M. (2017). Direct cytosolic delivery of CRISPR/Cas9-ribonucleoprotein for efficient gene editing. ACS Nano, 11(3), 2452-2458.